The NGAL Test™is a particle-enhanced turbidimetric immunoassay for the quantitative determination of NGAL in human urine, EDTA plasma or heparin plasma on automated clinical chemistry analyzers.

NGAL is a novel biomarker for the acute kidney injury (AKI)

NGAL (neutrophil gelatinase-associated lipocalin, lipocalin-2, siderocalin) is a small protein expressed in neutrophils and certain epithelia, including the renal tubules. Renal expression of NGAL is dramatically increased in kidney injury from a variety of causes, and NGAL is released into both urine and plasma. NGAL levels rise within 2 hours of the insult, making NGAL an early and sensitive biomarker of kidney injury.

Assay specifications

- Method Particle-enhanced immunoturbidimetric assay

- Sample Urine, EDTA plasma and heparin plasma

- Measuring range 25 to 5,000 ng/mL

- Security range Up to 40,000 ng/mL

- Assay time 10 minutes (Hitachi 917) (Can Vary Based On Analyzer Model)

- Shelf life 12 month

- Open vial stability 30 days

- On board stability 30 days (when refrigerated)