BioPorto Diagnostics proudly introduces a new Rat NGAL ELISA Kit replacing KIT 041

Since the first rat NGAL ELISA reached market in 2008, accumulated knowledge and continued developments have led to improvements of the assay performance. The name of the assay remains Rat NGAL ELISA kit, but with the improvements on the general assay performance BioPorto Diagnostics also introduces a new product number for the Rat NGAL ELISA Kit - KIT 046.

Featured changes in Rat NGAL ELISA Kit (KIT 046):

• Improved sensitivity - higher sensitivity allowing better discrimination between samples
• Improved calibration - metric values readout (pg/mL)
• Improved linearity - better sample dilution linearity

Rat NGAL - a biomarker of nephrotoxicity in drug development

Early kidney injury detection has been long sought and NGAL has recently been shown to be the biomarker that could fill this diagnostic gap. Measured from baseline, NGAL levels rise significantly in both urine and blood as a response to kidney injury – nephrotoxic, ischemic or otherwise.

Applicability

The Rat NGAL ELISA Kit allows for the determination of rises in rat NGAL concentrations and hence the extent of renal injury, including nephrotoxic injury. For example in the following phases of drug development:

• Discovery
• Research and development
• Pre-clinical phase

Kit features

• Simple ELISA format - easy to perform
  
  • Ready-to-use calibrators and working solutions
  • Pre-coated 96-well ELISA plate
  • All incubations performed at room temperature
• Easy storage
  
  • All components are stored at 4°C
• Automation possible on open ELISA workstations