Anti-GLP-1(7-37) and GLP-1(7-36)amide (N-terminal specific)
Mouse monoclonal antibody
Cat.No. ABS 033-04
Preparation: Protein-A purified
Content: Available in 200 μL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
Glucagon-like peptide 1(7-36)amide (GLP-1(7-36)amide) is the principal active form of GLP-1, the other
being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the
intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of
glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian
species examined so far.
Synthetic GLP-1(7-17) adsorbed onto aluminum hydroxide gel
ABS 033-04 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2%
cross-reactivity with GLP-1(1-37), GLP-1(9-36)amide, glucagon, human GIP and exendin-4.
Cross-reacts approximately 1% with human GLP-2.
Free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide.
ABS 033-04 binds free GLP-1(7-37) and free GLP-1(7-36)amide in solution. The ELISA dilution guideline
to GLP-1(7-37) coated directly at 1 μg/mL. Not recommended for use in sandwich ELISA.
| Method | Usability | References |
| ELISA | Yes | |
| Immunoblotting | Not determined | |
| Immunohistochemistry | Not determined |
Downloads
ABS 033-04.pdf (29.91 kB) Product specification
GLP-1 and Exendin-4 brochure.pdf (632.23 kB)
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