Anti-Glucagon (human, pig, rat)
Mouse Monoclonal Antibody
Cat.No. ABS 061-09
Preparation: Protein-A/G purified
Content: Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
Glucagon is a peptide hormone of 29 amino-acid residues produced by the alpha cells of the pancreatic islets. Its effect is to raise blood sugar as a stress hormone and counter-regulatory hormone for insulin. It is produced by cell-type-specific processing of proglucagon, which in the alpha cells is split to form glicentin-related pancreatic polypeptide, glucagon and major proglucagon fragment, while the same precursor is split to form glicentin, oxyntomodulin (C-terminally extended glucagon-37), GLP-1 and GLP-2 in the L cells of the intestinal mucosa.
Synthetic C-terminal fragment of glucagon coupled to carrier
ABS 061-09 binds human glucagon. Cross-reacts less than 5% with oxyntomodulin.
The epitope lies within the C-terminal region of glucagon.
ABS 061-09 binds free glucagon in solution.
ABS 061-09 when used as capture antibody forms a sandwich ELISA pair with ABS 058-08 as biotinylated detection antibody for measuring glucagon.
| Method | Usability | References |
| ELISA | Yes | |
| Immunoblotting | Not Determined | |
| Immunohistochemistry | Not Determined |
