Anti-Glucagon (human, pig, rat)
Mouse Monoclonal Antibody, Biotinylated
Cat.No. ABS 058-08B
Preparation: Biotinylated
Content: 50 μL, 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Solvent: 0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
Glucagon is a peptide hormone of 29 amino-acid residues produced by the alpha cells of the pancreatic islets. Its effect is to raise blood sugar as a stress hormone and counter-regulatory hormone for insulin. It is produced by cell-type-specific processing of proglucagon, which in the alpha cells is split to form glicentin-related pancreatic polypeptide, glucagon and major proglucagon fragment, while the same precursor is split to form glicentin, oxyntomodulin (C-terminally extended glucagon-37), GLP-1 and GLP-2 in the L cells of the intestinal mucosa.
Synthetic N-terminal fragment of glucagon coupled to carrier
ABS 058-08 binds human glucagon
The epitope lies within the N-terminal half of human glucagon
ABS 058-08 binds free glucagon in solution.
ABS 058-08 (as biotinylated detection antibody) forms a sandwich ELISA pair with ABS 061-09 (as capture antibody) for measuring glucagon.
| Method | Usability | References |
| ELISA | Yes | |
| Immunoblotting | Not Determined | |
| Immunohistochemistry | Not Determined |
