Anti-TAT (Thrombin-antithrombin)

Cat.No. ABS 014-22

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Cat. No.
ABS 014-22
Product name
Anti-TAT (Thrombin-antithrombin)
Description

Mouse monoclonal antibody

Specificity

ABS 014-22 is specific for human Thrombin-antithrombin (TAT) complexes

Immunogen

Thrombin-antithrombin (TAT) complexes

Application
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass

IgG1/k

Gene ID
2147
Clone number
22
Epitope

Not determined

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Thrombin (Factor IIa) is an enzyme, a serine protease, which participates in blood clotting. It is formed when prothrombin (Factor II) is proteolytically cleaved to form thrombin, which is glycoprotein formed by two peptides chains of 36 and 259 amino acids. Thrombin converts soluble fibrinogen into insoluble strands of fibrin and is then neutralized by antithrombin in order to for a thrombin-antithrombin (TAT) complex.
 
Application 1
ELISA
In a sandwich ELISA setup, ABS 014-222 acts as a capture antibody in conbination with HYB 230-01B as the detection antibody to measure TATcomplexes.
 
 
The calibration curve of a sandwich assay for TAT (Thrombin-antithrombin) using ABS 014-22 as capture antibody and HYB 230-01B as the biotinylated detection antibody.  
Application 2

IHC

ABS 014-22 was used in IHC on human tonsil tissue.

IHC staining of human tonsil tissue. Moderate staining intensity of the plasma of the veins. Dilution: 1:30