Anti-Procollagen type I C-terminal propeptide (human, PICP)

Cat.No. BTE 002-18

Buy online
Cat. No.
BTE 002-18
Product name
Anti-Procollagen type I C-terminal propeptide (human, PICP)
Description

Mouse monoclonal antibody

Specificity

BTE 002-08 is specific for native human PICP.

Immunogen

PICP purified from second-trimester amniotic fluid by affinity chromatography.

Application
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass

IgG1/k

Gene ID
1277
Clone number
18
Epitope

Epitope differs from that of BTE 002-08

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target

Type I collagen is present in connective tissue and bone where it makes up about 90% of the organic matrix. Type I collagen is produced from type-I procollagen by the proteolytic cleavage of N- and C-telopeptides, which are released into the circulation. The propeptides can be measured in serum as markers of the production of trype-I collagen. Elevated values of these propeptides are found in serum from patients with various metabolic or malignant bone diseases. Procollagen type I C-terminal propeptide (PICP) has a molecular mass of approximately 100 kDa. Its normal concentration in serum depends on age and sex.

Application 1

ELISA
BTE 002-18 is especially well suited as detecting antibody in a sandwich ELISA in combination with BTE 002-08.

Application 2

WB
BTE 002-18 can be used in Western blotting.

Application 3

IP

BTE 002-18 can be used in Immunoprecipitation.