Anti-Procollagen type I C-terminal propeptide (human, PICP)

Cat.No. BTE 002-08

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Cat. No.
BTE 002-08
Product name
Anti-Procollagen type I C-terminal propeptide (human, PICP)
Description

Mouse monoclonal antibody

Specificity

BTE 002-08 is specific for for native PICP from amniotic fluid.

Immunogen

PICP purified from second trimester amniotic fluid by affinity chromatography

Application
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass

IgG1/k

Gene ID
1277
Clone number
8
Epitope

Epitope differs from that of BTE 002-18

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target

Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organix matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of approximately 100 kDa and the normal range in serum is 100-300µg/ml

Application 1

ELISA
BTE 002-08 is especially well suited as catching antibody in a sandwich ELISA in combination with BTE 002-18.

Application 2

IP
BTE 002-08 can be used in Immunoprecipitation.