Cat.No. ABS 054-14
ABS 054-14B binds human GIP (3-42).
Synthetic human gastric inhibitory polypeptide
Available in 200 μL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Human gastric inhibitory polypeptide (GIP) is a 42 amino acid peptide belonging to the glucagon-secretin
family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates
glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the
intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from
approximately 50% identity for glucagon to 30% identity for GLP-2).
ABS 057-25 (as capture antibody) forms a sandwich ELISA pair with ABS 054-14B (as biotinylated
detection antibody) for measuring GIP. Data suggest that this matched antibody pair is the most sensitive
pair for measuring GIP (3-42). Detection limit obtained with our non-optimized buffer system is up to 1
ng/mL of GIP (3-42). Cross-reaction with GIP (1-42) is around 2%.