Cat.No. ABS 004-22
Mouse monoclonal antibody
ABS 004-22 is specific for complement factor C9
Complement factor C9
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Complement factor C9 is a 71kDa single-chain ellipsoid a-globular molecule of 558 amino acids including a leader sequence of 20 amino acids. C9 bind the C5b8 complex on membranes and has an unique property in forming tubular structures containing between 12 and 18 monomers, closely resembling the membrane attack complex (MAC). The primary site of synthesis is hepatocytes, secondary sites are monocytes, fibroblasts and glial cells. The normal level of C9 in plasma is 60 µg/mL, and the level is up regulated from hepatocytes by IFN-g.
ABS 004-22 can be used in Western blotting.
ABS 004-22 can be used in IHC.
|IHC staining of human liver with ABS 004-22. Plasma of portal veins are strongly stained. Dilution: 1:100.|
|IHC staining of tonsil tissue with ABS 004-22. Follicular dendritic cell network stained strongly in germinal centers of tonsil tissue. Also moderate staining were observed from plasma of veins. Dilution: 1:100.|
ABS 004-22 can be used in IF.
|IF staining of tonsil tissue with ABS 004-22. Follicular dendritic cell network stained strongly in germinal centers of tonsil tissue. Dilution: 1:75.|
|IF staining of human kidney with ABS 004-22. Plasma of veins are strongly stained. Dilution: 1:75.|