Rat NGAL ELISA Kit

Cat.No. KIT 046

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Cat. No.
KIT 046
Product name
Rat NGAL ELISA Kit
Description

A quantitative assay for the in vitro determination of rat NGAL in urine, plasma, serum, tissue extracts or culture media. 

Assay range

4-400 pg/mL

Assay time
<4 hours
Limit of detection

0.5 pg/mL

Sample dilution
1/20,000 (Urine or EDTA plasma, healthy rats)
Species reactivity (positive)
None
Storage
4°C
Target

Rat NGAL (Neutrophil Gelatinase-Associated Lipocalin)

Background

NGAL determination allows kidney injury to be detected almost as soon as it occurs, and not at the later stage when the consequences of impaired kidney function can be detected by existing routine tests and the damage has been consolidated.

Regulatory status
RUO - Research Use Only.
Other information
Kit features Highly reproducible and easy to use Ready-to-use working solutions Ready-to-use calibrators Pre-coated 96-well ELISA plate All incubations performed at room temperature Easy storage All components are stored at 4°C Requires only standard ELISA equipment

Pai MP, Chen WZ, Garba A, Cui H, Zaffo B, El-Fawal HA, Mousa SA (2013) Effects of obesity and sex on antimicrobial pharmacokinetics and acute kidney injury: validation of a preclinical model. Antimicrob Agents Chemother. 57:716-722

Sohotnik R, Nativ O, Abbasi A, Awad H, Frajewicki V, Bishara B, Sukhotnik I, Armaly Z, Aronson D, Heyman SN, Nativ O, Abassi Z (2013) Phosphodiesterase-5 inhibition attenuates early renal ischemia-reperfusion-induced acute kidney injury: assessment by quantitative measurement of urinary NGAL and KIM-1. Am J Physiol Renal Physiol. 304:1099-1104

Sultan S, Cameron S, Ahmad S, Malik IA, Schultze FC, Hielscher R, Rave-Frank M, Hess CF, Ramadori G, Christiansen H (2013) Serum Lipocalin2 is a potential biomarker of liver irradiation damage. Liver Int. 33:459-468

Bohn AB, Norregaard R, Stodkilde L, Wang Y, Bertelsen LB, Fenton RA, Matchkov VV, Bouzinova EV, Horsman MR, Frokiaer J, Stodkilde-Jorgensen H (2012) Treatment with the vascular disrupting agent combretastatin is associated with impaired AQP2 trafficking and increased urine output. Am J Physiol Regul Integr Comp Physiol. 303:186-198

Giani JF, Burghi V, Veiras LC, Tomat A, Munoz MC, Cao G, Turyn D, Toblli JE, Dominici FP (2012) Angiotensin-(1-7) attenuates diabetic nephropathy in Zucker diabetic fatty rats. Am J Physiol Renal Physiol. 302:1606-1615