Anti-NGAL(human)

Cat.No. ABS 038-04

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Cat. No.
ABS 038-04
Product name
Anti-NGAL(human)
Description

Mouse monoclonal antibody

Specificity

ABS 038-04 binds human NGAL (neutrophil gelatinase-associated lipocalin)

Immunogen

Recombinant human NGAL 

Application
Species reactivity (positive)
Human
Species reactivity (negative)
Dog. pig, mouse, rat
Subclass

IgG1/k

Gene ID
3934
Clone number
04
Epitope

Differs from those of HYB 211-01, ABS 038-14, -15 and the ABS 062 series of antibodies.

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target

Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury.

Application 1
ELISA
ABS 038-04 binds human NGAL in solution and coated onto a solid phase. 
ABS 038-04 (as capture antibody) forms sandwich pairs with HYB 211-01, ABS 038-14 and ABS 038-15 (as biotinylated detection antibodies) for measuring human NGAL.
Application 2

WB
ABS 038-04 can be used in Western blotting.