Cat.No. ABS 046-03B
Mouse monoclonal antibody, biotinylated
C-terminus of GLP-1(1-37), GLP-1(7-37) and GLP-1(9-37)
50 µL, 1 mg/mL +/- 15%. See Certificate of Analysis for details.
GLP-1(7-36) amide is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
ABS 046-03B as a biotinylated detection antibody and HYB 147-12 as a capture antibody cross- reacting about 16% with C-terminally amidated GLP-1. Results show detection limits of 44pmol/L which is 10-20 times higher than the basal concentration of GLP-1, so the assays have to be optimized.