Anti-GLP-1 (Mid-molecule specific)

Cat.No. HYB 147-08B

Cat. No.
HYB 147-08B
Product name
Anti-GLP-1 (Mid-molecule specific)
Description

Mouse monoclonal antibody, biotinylated

Specificity

Reacts with all forms of GLP-1, including precursor and GLP-1(9-37) /GLP-1(9-36amide) metabolite. HYB 147-08 cross-reacts with Liraglutide. 

Immunogen

Synthetic GLP-1(7-36)amide coupled to carrier

Application
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass

IgG2a/k

Gene ID
2641
Clone number
11E2
Epitope

Mid-molecular epitope of GLP-1

Content

50 µL, 1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification
Biotinylated
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target

Glucagon-like peptide 1(7-36)amide (GLP-1(7-36)amide) is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.

Application 1

ELISA

HYB 147-08 can be used as a detection antibody in ELISA.