Cat.No. HAH 002-01B
Mouse monoclonal antibody, biotinylated
HAH 002-01 is specific for butyrylcholinesterase from human serum or plasma.
Butyrylcholinesterase isolated from human plasma
50 µL, 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Butyrylcholinesterase (BChE, EC 22.214.171.124.) is synthetizised in the liver, and is predominantly found in serum, liver and pancreas. Butyrylcholinesterase is a tetrameric glycoprotein (molecular mass of 350 kDa), and consists of four subunits, each with molecular mass of 90 kDa.
|The calibration curve of a sandwich assay for Butyrylcholinesterase using HAH 002-01 as the capture antibody and HAH 002-01B as the biotinylated detection antibody.|
1. Aoki Y, Helzlsouer K, Strickland P (2014) Arylesterase Phenotype-Specific Positive Association Between Arylesterase Activity and Cholinesterase Specific Activity in Human Serum. Int. J. Environ. Res. Public Health 11:1422-1443.
2. Pan Y, Gao D, Yang W, Cho H, Yang G, Tai HH, Zhan CG (2005) Computational redesign of human butyrylcholinesterase for anticocaine medication. Proc Natl Acad Sci 102:16656-61.
3. Yang W, Pan Y, Zheng F, Cho H, Tai HH, Zhan CG (2009) Free-Energy Perturbation Simulation on Transition States and Redesign of Butyrylcholinesterase. Biophysical Journal 96:1931-1938.
4. Sporty J, Lemire S, Jakubowski E, Renner J, Evans R, Williams R, Schmidt J, van der Schans M, Noort D, Johnson R (2010) Immunomagnetic Separation and Quantification of Butyrylcholinesterase Nerve Agent Adducts in Human Serum. Anal Chem 82, 6593-6600.
5. Knaack J, Zhou Y, Abney C, Prezioso S, Magnuson M, Evans R, Jakubowski E, Hardy K, Johnson R (2012) High-Throughput Immunomagnetic Scavenging Technique for Quantitative Analysis of Live VX Nerve Agent in Water, Hamburger, and Soil Matrixes. Anal Chem 84:10052-10057.