Cat.No. ABS 039-15
Mouse monoclonal antibody
ABS 039-15 binds rat NGAL (neutrophil gelatinase-associated lipocalin)
Recombinant rat NGAL precursor with C-terminal His-tag coupled to carrier
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Rat NGAL, so called because it is the ortholog of human neutrophil gelatinase-associated lipocalin (NGAL), is also called lipocalin 2, 25-kDa alpha 2-microglobulin-related protein or neu-related lipocalin. It is expressed by neutrophils and various epithelial cells, including tubular cells of the kidney. It is involved in physiological processes such as the binding of siderophore iron and tissue growth and regeneration. It is up-regulated in a variety of pathological situations including infection, inflammation, renal injury and certain adenocarcinomas.
|The figure illustrates the calibration curve of a sandwich assay with ABS 039-15 as the capture antibody and ABS 039-32B as the biotinylated detection antibody.|
1. Bangert et al (2013) The Monomer is the Major Form of NGAL in Urine and Plasma in Severe Sepsis J Am Soc Nephrol 24: 368A