Cat.No. BTE 002-18
Mouse monoclonal antibody
BTE 002-08 is specific for native human PICP.
PICP purified from second-trimester amniotic fluid by affinity chromatography.
Epitope differs from that of BTE 002-08
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Type I collagen is present in connective tissue and bone where it makes up about 90% of the organic matrix. Type I collagen is produced from type-I procollagen by the proteolytic cleavage of N- and C-telopeptides, which are released into the circulation. The propeptides can be measured in serum as markers of the production of trype-I collagen. Elevated values of these propeptides are found in serum from patients with various metabolic or malignant bone diseases. Procollagen type I C-terminal propeptide (PICP) has a molecular mass of approximately 100 kDa. Its normal concentration in serum depends on age and sex.
BTE 002-18 is especially well suited as detecting antibody in a sandwich ELISA in combination with BTE 002-08.
BTE 002-18 can be used in Western blotting.