Cat.No. ABS 062-14B
Mouse monoclonal antibody, biotinylated
ABS 062-14 is specific for human NGAL (neutrophil gelatinase-associated lipocalin)
Human recombinant NGAL coupled to carrier
Differs from those of HYB 211-01, the ABS 038 series of antibodies and ABS 062-33.
50 µL, 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury.
|The calibration curve of a sandwich assay for monomer human NGAL using ABS 062-33 as the capture antibody and ABS 062-14B as the biotinylated detection antibody. (1).|
1. Bangert et al (2013) The Monomer is the Major Form of NGAL in Urine and Plasma in Severe Sepsis J Am Soc Nephrol 24: 368A