Cat.No. ABS 058-08B
Mouse monoclonal antibody, biotinylated
ABS 058-08 binds human glucagon.
Synthetic N-terminal fragment of glucagon coupled to carrier
The epitope lies within the N-terminal half of human glucagon
50 µL, 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Glucagon is a peptide hormone of 29 amino-acid residues produced by the alpha cells of the pancreatic islets. Its effect is to raise blood sugar as a stress hormone and counter-regulatory hormone for insulin. It is produced by cell-type-specific processing of proglucagon, which in the alpha cells is split to form glicentin-related pancreatic polypeptide, glucagon and major proglucagon fragment, while the same precursor is split to form glicentin, oxyntomodulin (C-terminally extended glucagon-37), GLP-1 and GLP-2 in the L cells of the intestinal mucosa.
|The calibration curve of a sandwich assay for Glucagon using ABS 061-09 as the capture antibody and ABS 058-08B as the biotinylated detection antibody.|