Cat.No. HYB 147-13
Mouse monoclonal antibody
Reacts with all forms of GLP-1, including precursor and GLP-1(9-37) /GLP-1(9-36amide) metabolite. HYB 147-13 cross-reacts with Liraglutide.
Synthetic GLP-1(7-36)amide coupled to carrier
Mid-molecular epitope of GLP-1.
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Glucagon-like peptide 1(7-36)amide (GLP-1(7-36)amide) is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
In Western blotting a dilution guideline of 1/1000 has proved successful.
HYB 147-13 has been used in IHC.
|Formalin fixed paraffin-embedded human pancreas tissue stained with HYB 147-13. Alpha cells of the Langerhans islet and scattered cells in exocrine area of pancreas were stained strongly. Dilution: 1:3200|
|Formalin fixed paraffin-embedded human liver tissue stained with HYB 147-13. Hepatocytes were stained strongly. Dilution: 1:3200|
HYB 147-13 has been used in IF.
|IF staining in human pancreas tissue stained with HYB 147-13. Signal is strong in alpha cells. Dilution: 1:4000.|
|IF staining in human liver tissue stained with HYB 147-13. Signal is strong in the cytoplasmic site of hepatocytes. Dilution: 1:4000.|