Anti-Fibronectin (human)

Cat.No. HYB 051-05

Cat. No.
HYB 051-05
Product name
Anti-Fibronectin (human)
Description

Mouse monoclonal antibody

Specificity

HYB 051-05 has specificity for human fibronectin

Immunogen

Fibronectin isolated from human plasma 

Application
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass

IgG1/l

Gene ID
2335
Clone number
3D2
Epitope

Not determined

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target

Fibronectin is an adhesive glycoprotein with a molecular mass of 440 kDa. It is believed to be important for the formation of a provisional matrix that promotes cell adhesion and migration during wound healing. Its age-dependent increase in plasma and tissues may be accompanied in pathological states, especially in tumor growth, by its proteolytic breakdown by a number of neutral proteases. It has also shown that several of its proteolytic breakdown products exhibit unexpected and mostly harmful biological activities.

Application 1

ELISA

HYB 051-05 reacts strongly with fibronectin. A strong reaction is seen in ELISA with fibronectin directly coated onto the microtiter plate.
Application 2

WB

In Western blot after SDS-PAGE, HYB 051-05 reacts with fibronectin in reduced as well as in nonreduced form.